Simon Hogan, PhD, Associate Professor

Division of Allergy and Immunology
Cincinnati Children’s Hospital Medical Center

E-Mail: simon.hogan(at)cchmc.org
Tel.: 001 513 636 6620

Recent publications:

1. Zhu X, Hogan SP, Molkentin JD, Zimmermann N. Cyclophilin D Regulates Necrosis But Not Apoptosis of Murine Eosinophils. Am J Physiol Gastrointest Liver Physiol.2016 Feb 18:ajpgi.00389.2015. PubMed PMID: 26893161.

2. Sledd J, Wu D, Ahrens R, Lee J, Waggoner L, Tsai YT, Wang YH, Hogan SP. Loss of IL-4Rα-mediated PI3K signaling accelerates the progression of IgE/mast cell-mediated reactions. Immun Inflamm Dis. 2015 Sep 17;3(4):420-30. PubMed PMID: 26734464.

3. Waddell A, Vallance JE, Moore PD, Hummel AT, Wu D, Shanmukhappa SK, Fei L,Washington MK, Minar P, Coburn LA, Nakae S, Wilson KT, Denson LA, Hogan SP, Rosen MJ. IL-33 Signaling Protects from Murine Oxazolone Colitis by Supporting Intestinal Epithelial Function. Inflamm Bowel Dis. 2015 Dec;21(12):2737-46. PubMed PMID: 26313694.

4. Lee JB, Chen CY, Liu B, Mugge L, Angkasekwinai P, Facchinetti V, Dong C, LiuYJ, Rothenberg ME, Hogan SP, Finkelman FD, Wang YH. IL-25 and CD4(+) T(H)2 cells enhance type 2 innate lymphoid cell-derived IL-13 production, which promotes IgE-mediated experimental food allergy. J Allergy Clin Immunol. 2015 Nov 9. PubMed PMID: 26560039.

5. Chen CY, Lee JB, Liu B, Ohta S, Wang PY, Kartashov AV, Mugge L, Abonia JP,
Barski A, Izuhara K, Rothenberg ME, Finkelman FD, Hogan SP, Wang YH. Induction of Interleukin-9-Producing Mucosal Mast Cells Promotes Susceptibility to IgE-Mediated Experimental Food Allergy. Immunity. 2015 Oct 20;43(4):788-802. PubMed PMID: 26410628.

6. D'Mello RJ, Caldwell JM, Azouz NP, Wen T, Sherrill JD, Hogan SP, Rothenberg
ME. LRRC31 is induced by IL-13 and regulates kallikrein expression and barrier function in the esophageal epithelium. Mucosal Immunol. 2015 Oct 14. PubMed PMID: 26462420.

7: Zhu X, Mose E, Hogan SP, Zimmermann N. Differential eosinophil and mast cell regulation: mast cell viability and accumulation in inflammatory tissue are independent of proton-sensing receptor GPR65. Am J Physiol Gastrointest Liver Physiol. 2014 Jun 1;306(11):G974-82. PubMed PMID: 24742990.

8: Sherrill JD, Kc K, Wu D, Djukic Z, Caldwell JM, Stucke EM, Kemme KA, Costello MS, Mingler MK, Blanchard C, Collins MH, Abonia JP, Putnam PE, Dellon ES, Orlando RC, Hogan SP, Rothenberg ME. Desmoglein-1 regulates esophageal epithelial barrier function and immune responses in eosinophilic esophagitis. Mucosal Immunol. 2014 May;7(3):718-29. PubMed PMID: 24220297.

9: Lampinen M, Waddell A, Ahrens R, Carlson M, Hogan SP. CD14+CD33+ myeloid cell-CCL11-eosinophil signature in ulcerative colitis. J Leukoc Biol. 2013 Nov;94(5):1061-70. PubMed PMID: 23904440.

10: Waddell A, Ahrens R, Tsai YT, Sherrill JD, Denson LA, Steinbrecher KA, HoganSP. Intestinal CCL11 and eosinophilic inflammation is regulated by myeloid cell-specific RelA/p65 in mice. J Immunol. 2013 May 1;190(9):4773-85. PubMed PMID: 23562811.

See all Publications on PubMed