Prof. Dr. med. Jan Rupp

Department of Infectious Diseases and Microbiology
University of Lübeck

E-Mail: jan.rupp(at)
Tel.: 0049 451 500 45300

Recent publications:

1: Quäschling, T., Friedrich, D., Deepe Jr. G. S., Rupp, J. 2020. Crosstalk between autophagy and hypoxia-inducible factor-1α in antifungal immunity. Cells. 9, 2150. PMID: 32977563

2: Szaszák M, Shima K, Käding N, Hannus M, Solbach W, Rupp J. Host metabolism promotes growth of Chlamydia pneumoniae in a low oxygen environment. Int J MedMicrobiol. 2013 Jul;303(5):239-46. PubMed PMID: 23665044.

3: Rotta Detto Loria J, Rohmann K, Droemann D, Kujath P, Rupp J, Goldmann T,Dalhoff K. Nontypeable Haemophilus Influenzae Infection Upregulates the NLRP3 Inflammasome and Leads to Caspase-1-Dependent Secretion of Interleukin-1beta - A Possible Pathway of Exacerbations in COPD. PLoS One. 2013 Jun 26;8(6):e66818.Print 2013. PubMed PMID: 23840534.

4: Shima K, Klinger M, Solbach W, Rupp J. Activities of first-choice antimicrobials against gamma interferon-treated Chlamydia trachomatis differ in hypoxia. Antimicrob Agents Chemother. 2013 Jun;57(6):2828-30. PubMed PMID: 23478971.

5: Szaszák M, Chang JC, Leng W, Rupp J, Ojcius DM, Kelley AM. Characterizing the intracellular distribution of metabolites in intact Chlamydia-infected cells by Raman and two-photon microscopy. Microbes Infect. 2013 Jun;15(6-7):461-9. PubMed PMID: 23541981.

6: Haas CS, Lehne W, Muck P, Boehm A, Rupp J, Steinhoff J, Lehnert H. Acute kidney injury and thrombocytopenic fever--consider the infrequent causes. Am JEmerg Med. 2013 Feb;31(2):441.e5-9. PubMed PMID:23407036.

7: Jerchel S, Knebel G, König P, Bohlmann MK, Rupp J. A human fallopian tube model for investigation of C. trachomatis infections. J Vis Exp. 2012 Aug11;(66). PubMed PMID: 22907315.

8: Dietz I, Jerchel S, Szaszák M, Shima K, Rupp J. When oxygen runs short: the microenvironment drives host-pathogen interactions. Microbes Infect. 2012Apr;14(4):311-6. Review.PubMed PMID: 22133978.

9: Nitschke M, Sayk F, Härtel C, Roseland RT, Hauswaldt S, Steinhoff J,Fellermann K, Derad I, Wellhöner P, Büning J, Tiemer B, Katalinic A, Rupp J,Lehnert H, Solbach W, Knobloch JK. Association between azithromycin therapy and duration of bacterial shedding among patients with Shiga toxin-producing enteroaggregative Escherichia coli O104:H4. JAMA. 2012 Mar 14;307(10):1046-52. PubMed PMID: 22416100.

10: Szaszák M, Steven P, Shima K, Orzekowsky-Schröder R, Hüttmann G, König IR,Solbach W, Rupp J. Fluorescence lifetime imaging unravels C. trachomatis metabolism and its crosstalk with the host cell. PLoS Pathog. 2011Jul;7(7):e1002108. PubMed PMID: 21779161.

11: Shima K, Szaszák M, Solbach W, Gieffers J, Rupp J. Impact of a low-oxygen environment on the efficacy of antimicrobials against intracellular Chlamydia trachomatis. Antimicrob Agents Chemother. 2011 May;55(5):2319-24. PubMed PMID: 21321137.

See all publications on PubMed