Prof. Dr. rer. nat. Frank Petersen

Division of Immunoregulation
Research Center Borstel

E-Mail: fpetersen(at)
Tel.: 0049 4537 1884510

Recent publications:

1: Zheng J, Yin J, Huang R, Petersen F, Yu X. Meta-analysis reveals an association of STAT4 polymorphisms with systemic autoimmune disorders and anti-dsDNA antibody. Hum Immunol. 2013 Apr 27. PubMed PMID: 23628400.

2: Zheng J, Ibrahim S, Petersen F, Yu X. Meta-analysis reveals an association of PTPN22 C1858T with autoimmune diseases, which depends on the localization of the affected tissue. Genes Immun. 2012 Dec;13(8):641-52. PubMed PMID: 23076337.

3: Schwartzkopff F, Petersen F, Grimm TA, Brandt E. CXC chemokine ligand 4(CXCL4) down-regulates CC chemokine receptor expression on human monocytes. Innate Immun. 2012 Feb;18(1):124-39. Erratum in: Innate Immun. 2013 Feb;19(1):112. PubMed PMID: 21088050.

4: Kasper B, Petersen F. Molecular pathways of platelet factor 4/CXCL4 signaling. Eur J Cell Biol. 2011 Jun-Jul;90(6-7):521-6. Review. PubMed PMID: 21295372.

5: Kasper B, Winoto-Morbach S, Mittelstädt J, Brandt E, Schütze S, Petersen F. CXCL4-induced monocyte survival, cytokine expression, and oxygen radical formation is regulated by sphingosine kinase 1. Eur J Immunol. 2010 Apr;40(4):1162-73. PubMed PMID: 20104488.

6: Schiemann F, Brandt E, Gross R, Lindner B, Mittelstädt J, Sommerhoff CP,Schulmistrat J, Petersen F. The cathelicidin LL-37 activates human mast cells and is degraded by mast cell tryptase: counter-regulation by CXCL4. J Immunol. 2009 Aug 15;183(4):2223-31. PubMed PMID: 19625657.

7: Woller G, Brandt E, Mittelstädt J, Rybakowski C, Petersen F. Platelet factor4/CXCL4-stimulated human monocytes induce apoptosis in endothelial cells by the release of oxygen radicals. J Leukoc Biol. 2008 Apr;83(4):936-45. PubMed PMID: 18203873.

8: Kasper B, Brandt E, Brandau S, Petersen F. Platelet factor 4 (CXC chemokine ligand 4) differentially regulates respiratory burst, survival, and cytokine expression of human monocytes by using distinct signaling pathways. J Immunol.2007 Aug 15;179(4):2584-91. PubMed PMID: 17675521.

9: Schiemann F, Grimm TA, Hoch J, Gross R, Lindner B, Petersen F, Bulfone-Paus S,Brandt E. Mast cells and neutrophils proteolytically activate chemokine precursor CTAP-III and are subject to counterregulation by PF-4 through inhibition of chymase and cathepsin G. Blood. 2006 Mar 15;107(6):2234-42. Epub 2005 Nov 29.PubMed PMID: 16317101.

10: Kasper B, Brandt E, Ernst M, Petersen F. Neutrophil adhesion to endothelialcells induced by platelet factor 4 requires sequential activation of Ras, Syk,and JNK MAP kinases. Blood. 2006 Mar 1;107(5):1768-75. PubMedPMID: 16263791.

See all publications on PubMed