David A. Hildeman, PhD, Associate Professor

Division of Cellular and Molecular Immunology
Cincinnati Children’s Hospital Medical Center

E-Mail: david.hildeman(at)cchmc.org
Tel.: 001 513 803 1056

Recent publications:

1. Kuethe JW, Armocida SM, Midura EF, Rice TC, Hildeman DA, Healy DP, Caldwell CC. Fecal Microbiota Transplant Restores Mucosal Integrity in a Murine Model of Burn Injury. Shock. 2015 Dec 14. [Epub ahead of print] PubMed PMID: 26682948.

2. Raynor J, Karns R, Almanan M, Li KP, Divanovic S, Chougnet CA, Hildeman DA. IL-6 and ICOS Antagonize Bim and Promote Regulatory T Cell Accrual with Age. JImmunol. 2015 Aug 1;195(3):944-52. PubMed PMID: 26109645.

3. Lampe K, Endale M, Cashman S, Fang H, Mattner J, Hildeman D, Hoebe K. Slp-76is a critical determinant of NK-cell mediated recognition of missing-selftargets. Eur J Immunol. 2015 Jul;45(7):2072-83. PubMed PMID: 25929249.

4: Niss O, Sholl A, Bleesing JJ, Hildeman DA. IL-10/Janus kinase/signal transducer and activator of transcription 3 signaling dysregulates Bim expression in autoimmune lymphoproliferative syndrome. J Allergy Clin Immunol. 2015 Mar;135(3):762-70. PubMed PMID: 25174872.

5: Kurtulus S, Sholl A, Toe J, Tripathi P, Raynor J, Li KP, Pellegrini M, Hildeman DA. Bim controls IL-15 availability and limits engagement of multiple BH3-only proteins. Cell Death Differ. 2015 Jan;22(1):174-84. PubMed PMID: 25124553.

6: Herold MJ, Stuchbery R, Mérino D, Willson T, Strasser A, Hildeman D, Bouillet P. Impact of conditional deletion of the pro-apoptotic BCL-2 family member BIM in mice. Cell Death Dis. 2014 Oct 9;5:e1446. PubMed PMID: 25299771.

7: McNally JP, Elfers EE, Terrell CE, Grunblatt E, Hildeman DA, Jordan MB, Katz JD. Eliminating encephalitogenic T cells without undermining protective immunity. J Immunol. 2014 Jan 1;192(1):73-83. Erratum in: J Immunol. 2014 Mar 1;192(5):2522. PubMed PMID: 24277699.

8: Johnson TS, Terrell CE, Millen SH, Katz JD, Hildeman DA, Jordan MB. Etoposide  selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis. J Immunol. 2014 Jan 1;192(1):84-91. PubMed PMID: 24259502.

9: Pierson W, Cauwe B, Policheni A, Schlenner SM, Franckaert D, Berges J,Humblet-Baron S, Schönefeldt S, Herold MJ, Hildeman D, Strasser A, Bouillet P, LuLF, Matthys P, Freitas AA, Luther RJ, Weaver CT, Dooley J, Gray DH, Liston A. Anti apoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3(+) regulatory T cells. Nat Immunol. 2013 Jul 14. PubMed PMID: 23852275.

10: Tripathi P, Koss B, Opferman JT, Hildeman DA. Mcl-1 antagonizes Bax/Bak topromote effector CD4(+) and CD8(+) T-cell responses. Cell Death Differ. 2013 Apr 5. PubMed PMID: 23558951.

See all publications on PubMed