Latest Publications

 

2019

Twisselmann N, Bartsch YC, Pagel J, Wieg C, Hartz A, Ehlers M, Härtel C. IgG Fc Glycosylation Patterns of Preterm Infants Differ With Gestational Age. Front Immunol. 2019 Jan 18; 9:3166. doi: 10.3389/fimmu.2018.03166. PMID: 30713537

 


 

2018

Graspeuntner S, Waschina S, Künzel S, Twisselmann N, Rausch TK, Cloppenborg-Schmidt K, Zimmermann J, Viemann D, Herting E, Göpel W, Baines JF, Kaleta C, Rupp JHärtel CPagel J. Gut dysbiosis with Bacilli dominance and accumulation of fermentation products precedes late-onset sepsis in preterm infants. Clin Infect Dis.2018 doi: 10.1093/cid/ciy882. PMID: 30329017

Hoffmann FM, Berger JL, Lingel ILaumonnier Y, Lewkowich IP, Schmudde I, and König P. Distribution and interaction of Murine Pulmonary Phagocytes in the naive and allergic lung. Frontiers in Immunology, 9:1046; 2018 PMID: 29868009

Eresso A, Arkajyoti M, Deepti R, Vasundhara M, Tejaswini P, van Zandbergen G, Solbach W, Dandapat J, Tackenberg H, Ohms M, Sarkar A, Laskay T. Type-1 interferons prolong the lifespan of neutrophils by interfering with members of the apoptotic cascade. Cytokine,Volume 112, 2018, Pages 21-26, ISSN 1043-4666. PMID: 30554594

Göpel W, Drese J, Rausch TK, Twisselmann N, Bohnhorst B, Müller A, Franz A, Ziegler A, Härtel C, Herting E. Necrotizing enterocolitis and high intestinal iron uptake due to genetic variants. Pediatr Res. 2018 Jan; 83(1-1):57-62. doi: 10.1038/pr.2017.195. PMID: 28820869


  

2017

Johnson BL 3rd, Midura EF, Prakash PS, Rice TC, Kunz N, Kalies K, Caldwell CC. Neutrophil derived microparticles increase mortality and the counter-inflammatoryresponse in a murine model of sepsis. Biochim Biophys Acta. 2017 Jan 17. pii:S0925-4439(17)30017-0. doi: 10.1016/j.bbadis.2017.01.012. [Epub ahead of print] PubMed PMID: 28108420

Karsten CM, Wiese AV, Mey FFigge JWoodruff TM, Reuter T, Scurtu O, Kordowski A, Almeida LN, Briukhovetska D, Quell KM, Sun J, Ender F, Schmudde I, Vollbrandt T, Laumonnier Y, Köhl JMonitoring C5aR2 Expression Using a Floxed tdTomato-C5aR2 Knock-In Mouse. J Immunol. 2017 Nov 1;199(9):3234-3248. doi: 10.4049/jimmunol.1700710. Epub 2017 Sep1. PMID: 28864475

 


 

2016

Milićević NM, Schmidt F, Kunz N, Kalies K, Milićević Ž, Schlosser A, Holmskov U, Sorensen GL, Westermann J. The role of microfibrillar-associated protein 4(MFAP4) in the formation and function of splenic compartments during embryonic and adult life. Cell Tissue Res. 2016 Jul;365(1):135-45.  PubMed PMID: 26899386

Pagel J, Hartz A, Figge J, Gille C, Eschweiler S, Petersen K, Schreiter L,Hammer J, Karsten CMFriedrich D, Herting E, Göpel W, Rupp J, Härtel C. Regulatory T cell frequencies are increased in preterm infants with clinicalearly-onset sepsis. Clin Exp Immunol. 2016 Aug;185(2):219-27. PubMed PMID: 27163159

Hoffmann F, Ender F, Schmudde I, Lewkowich IP, Köhl J, König P, Laumonnier Y. Origin, Localization, and Immunoregulatory Properties of Pulmonary Phagocytes in Allergic Asthma. Front Immunol. 2016 Mar 23;7:107. Review. PubMed PMID: 27047494. 

Midura EF, Prakash PS, Johnson BL 3rd, Rice TC, Kunz N, Caldwell CC. Impact ofcaspase-8 and PKA in regulating neutrophil-derived microparticle generation. Biochem Biophys Res Commun. 2016 Jan 22;469(4):917-22. PubMed PMID: 26707875

 


 

2015 

Köhl J, Moreno-Fernandez ME, Aliberti JGroeneweg SChougnet C. A novel rolefor the receptor of the complement cleavage fragment C5a, C5aR1, in CCR5-mediatedentry of HIV into macrophages. AIDS Res Hum Retroviruses. 2015 Nov 5. PubMed PMID: 26537334.

Bollinger T, Bollinger A, Gies S, Feldhoff L, Solbach W, Rupp J. Transcriptionregulates HIF-1α expression in CD4(+) T cells. Immunol Cell Biol. 2015 Jul 7. PubMed PMID: 26150319.

Karsten CM, Laumonnier Y, Eurich B, Ender F, Bröker K, Roy S, Czabanska A, Vollbrandt T, Figge JKöhl J. Monitoring and Cell-Specific Deletion of C5aR1 Using a Novel Floxed GFP-C5aR1 Reporter Knock-in Mouse. J Immunol. 2015 Jan 14. pii: 1401401.PubMed PMID: 25589074

McCarthy MK, Procario MC, Twisselmann N, Wilkinson JE, Archambeau AJ, Michele DE, Day SM, Weinberg JB. Proinflammatory effects of interferon gamma in mouse adenovirus 1 myocarditis. J Virol.; 89(1):468-79. doi: 10.1128/JVI.02077-14. PMID: 25320326


 

2014

Strait RT, Posgai MT, Mahler A, Barasa N, Jacob CO, Köhl JEhlers M, Stringer K, Shanmukappa SK, Witte D, Hossain MM, Khodoun M, Herr AB, Finkelman FD. IgG1protects against renal disease in a mouse model of cryoglobulinaemia. Nature.2014 Nov 2. PubMed PMID:25363774.

Engelke C, Wiese AV, Schmudde I, Ender F, Ströver HA, Vollbrandt T, König P, Laumonnier Y, Köhl J. Distinct roles of the anaphylatoxins C3a and C5a in dendritic cell-mediated allergic asthma. J Immunol. 2014 Dec 1;193(11):5387-401. PubMed PMID: 25355927.

Bollinger T, Gies S, Naujoks J, Feldhoff L, Bollinger A, Solbach W, Rupp J. HIF-1α- and hypoxia-dependent immune responses in human CD4+CD25high T cells and T helper 17 cells. J Leukoc Biol. 2014 Aug;96(2):305-12. PubMed PMID: 24664971

Berod L, Stüve P, Varela F, Behrends J, Swallow M, Kruse F, Krull F, Ghorbani P, Mayer CT, Hölscher C, Sparwasser T. Rapid rebound of the Treg compartment inDEREG mice limits the impact of Treg depletion on mycobacterial burden, butprevents autoimmunity. PLoS One. 2014 Jul 22;9(7):e102804.  PubMed PMID: 25050936.

Schmitz V, Almeida LN, Svensjö E, Monteiro AC, Köhl J, Scharfstein J. C5a and Bradykinin Receptor Cross-Talk Regulates Innate and Adaptive Immunity inTrypanosoma cruzi Infection. J Immunol. 2014 Oct 1;193(7):3613-23. Epub 2014 Sep 3. PubMed PMID: 25187655.

Bär F, Föh B, Pagel R, Schröder T, Schlichting H, Hirose M, Lemcke S, Klinger A, König P, Karsten CM, Büning J, Lehnert H, Fellermann K, Ibrahim SM, Sina C. Carboxypeptidase E modulates intestinal immune homeostasis and protects against experimental colitis in mice. PLoS One 2014. 9:1–9. PMID:25051500

 


 

2013

Hess C, Winkler A, Lorenz AK, Holecska V, Blanchard V, Eiglmeier S, Schoen AL, Bitterling J, Stoehr AD, Petzold D, Schommartz T, Mertes MM, Schoen CT, Tiburzy B, Herrmann A, Köhl J, Manz RA, Madaio MP, Berger M, Wardemann H, Ehlers M. T cell-independent B cell activation induces immunosuppressive sialylated IgG antibodies. J Clin Invest. 2013 Sep 3;123(9):3788-96. PMID:23979161

Kemper C, Köhl J. Novel roles for complement receptors in T cell regulation and beyond. Mol Immunol. 2013 Jun 21. PubMed PMID: 23796748.

Schmudde I, Laumonnier Y, Köhl J. Anaphylatoxins coordinate innate and adaptive immune responses in allergic asthma. Semin Immunol. 2013 May 19. PubMed PMID: 23694705.